Travel Health Service Cholera

Vaccine and prophylaxis

Cholera Vaccination

Vaccination schedule

There are several licensed killed oral cholera vaccines currently worldwide and the primary series consists of one to three doses of vaccines given at least one to two weeks apart depending on the type of vaccine and age of the vaccinee.


Cholera vaccine confers incomplete, unreliable protection of short duration and may convey a false sense of security to the vaccinee who would then pay less attention on hygiene issues. Therefore it is rarely recommended except for those at high risk e.g. aid workers. It is not officially required as a condition of entry of any country.

Adverse reactions

Fatigue, headache and mild gastrointestinal symptoms may occur. Serious reaction is rare.


Persons with a history of severe reactions to the vaccine previously should not be vaccinated.